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Process for the preparation of 3-amino-pyrrolidine

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专利名称:Process for the preparation of 3-amino-pyrrolidine derivatives

发明人:Spurr, Paul,Wang, Shaoning,Klinkhammer,

Uwe

申请号:EP01114294.0申请日:19990108公开号:EP1138672A1公开日:20011004

摘要:The invention is concerned with a process for the manufacture of 3-amino-pyrrolidine derivatives of the formula    wherein by converting a compound of theformula wherein in the presence of a primary amine of the formula RNH into thepyrrolidine derivative of the formula    wherein X and R have the aforementionedsignificances; which is subsequently reacted in the presence of RRNH under pressure.

申请人:Basilea Pharmaceutica AG

地址:c/o Rudolf Maag Neuhofweg 11 4102 Binningen CH

国籍:CH

代理机构:Kjellsaa-Berger, Hanny, Dr.

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