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NONCLASSICAL PYRROLO 2,3-D]PYRIMIDINE ANTIFOLATES

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专利名称:NONCLASSICAL PYRROLO 2,3-D]PYRIMIDINE ANTIFOLATES

发明人:JORDAN, CHRISTOPHER, L.,PATEL, VINOD,

F.,SOOSE, DANIEL, J.

申请号:EP97939567申请日:19970827公开号:EP0923287A4公开日:20010801

摘要:Nonclassical pyrrolo[2,3-d]pyrimidine antifolates are described and claimed.Also described and claimed is a rapid analog process which enables a quick work-up ofthe antifolate which avoids costly and time-consuming chromatographic separationtechniques. Also described and claimed are methods of treating susceptible neoplasmswith these nonclassical antifolates. Also described and claimed are methods of treatingpsoriasis and arthritis with these nonclassical antifolates.

申请人:ELI LILLY AND COMPANY

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