专利名称：Gastrin releasing peptide antagonists发明人：Heimbrook, David C.,Riemen, Mark W.,Oliff,
Allen,Saari, Walfred S.
申请号：EP89202946.3申请日：19891121公开号：EP0371543A3公开日：19901219
摘要：Small cell lung carcinoma (SCLC) cells contain gastrin releasing peptide (GRP)receptors. The response of the cells to GRP is rapid growth. We have found a group ofpeptide derivatives that act as GRP antagonists by blocking the binding of GRP to itsreceptor thereby inhibiting the growth of cells that are sensitive to the growthpromoting activity of GRP.
申请人：Merck & Co., Inc.
地址：126, East Lincoln Avenue P.O. Box 2000 Rahway New Jersey 07065-0900 US
国籍：US
代理机构：Cole, William Gwyn
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