Substituted amino acids, their use and preparation

专利名称：Substituted amino acids, their use and

preparation, and compositions containingthem

发明人：KRASTINAT, WALTER, DR. DIPL.-ING.,RIEDEL,

RICHARD, DR.,WOLF, HORST, DR. DIPL.-CHEM.

申请号：EP79101911.0申请日：19790612公开号：EP0006217B1公开日：19820331

摘要：Acyl (bicyclic aryl) - aminoalkanoic acids of the general formula I in which R<1>signifies an aliphatic or alicyclic hydrocarbon radical or an optionally substituted phenylgroup, A signifies an optionally substituted and/or hydrogenated bicyclic aryl radical andn signifies 3, 4 or 5, as well as their salts of inorganic or organic bases exert in warm-blooded animals a protective action on the stomach and an increase in the pancreaticsecretion, and in addition they exert an action on the liver and bile. Furthermore, theybring about an inhibition of the formation of glucose from lactate and pyruvate in theliver. They are suitable for the treatment and prophylaxis of diseases which a@attributed to disorders of the stomach or intestine or to reduced performances of thepancreas, bile and/or liver, or the treatment of diabetes. Processes for the production ofthe compounds and suitable pharmaceutical products are given.

申请人：BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH

地址：Postfach 10 03 10 D-78403 Konstanz DE

国籍：DE

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