Methods of immobilizing ligands on solid supports

专利名称：Methods of immobilizing ligands on solid

supports

发明人：Ezra S. Abrams,Tianhong Zhang,Slawomir

Mielewczyk,Brian C. Patterson

申请号：US09649637申请日：20000828公开号：US06492118B1公开日：20021210

专利附图：

摘要：A method is provided for immobilizing a ligand, e.g., a nucleic acid, on a solidsupport. The method includes providing a solid support containing an immobilized latent

thiol group, activating the thiol group, contacting the activated thiol group with a nucleicacid comprising an acrylamide functional group, and forming a covalent bond betweenthe two groups, thereby immobilizing the nucleic acid to the solid support. Kitscontaining the solid supports and method of utilizing the solid supports are alsoprovided.

申请人：MATRIX TECHNOLOGIES CORPORATION

代理机构：Wood, Herron & Evans, LLP

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