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6 Interpretations Of Utility And Their Implications For The Valuation Of Health

来源:六九路网
TheEconomicJournal,118(January),215–234.ÓTheAuthor(s).JournalcompilationÓRoyalEconomicSociety2008.PublishedbyBlackwellPublishing,9600GarsingtonRoad,OxfordOX42DQ,UKand350MainStreet,Malden,MA02148,USA.

INTERPRETATIONSOFUTILITYANDTHEIR

IMPLICATIONSFORTHEVALUATIONOFHEALTH*

PaulDolanandDanielKahneman

ThetermÔutilityÕcanbeinterpretedintermsofthehedonicexperienceofanoutcome(experiencedutility)orintermsofthepreferenceordesireforthatoutcome(decisionutility).Itisthissecondinterpretationthatliesattheheartofthemethodsthateconomistshavedevelopedtovaluenon-marketgoods,suchashealth.Inthisarticle,wearguethatdecisionutilityisunlikelytogeneratemeaningfuldataontheutilityassociatedwithdifferentexperiences,andinsteadeconomistsshouldlooktowardsdevelopingmeasuresthatfocusmoredirectlyonexperiencedutility.

Theconceptofutilityiscentraltobothnormativeanddescriptivedebatesineco-nomics.ThewordÔutilityÕhastwodistinctmeanings:itcanrefereithertothehedonicexperienceofanoutcomeortothepreferenceordesireforthatoutcome.Thesehavebeenlabelledexperiencedutilityanddecisionutility,respectively(Kahnemanetal.,1997).JeremyBenthamfirstdefinedutilityinhedonicterms,asameasureofpleasureandpain(Bentham,1789/1948),andeconomistsfollowedthatusageuntilthetwen-tiethcentury.FrancisEdgeworthevenimaginedaÔhedonimeterÕ,aninstrumentthatmeasurestheutilityofmomentsofexperienceandplotsexperiencedutilityasacon-tinuousfunctionoftime(Edgeworth,1881/1967).Heproposedthattheareaunderthecurverepresentstheindividual’stotalhappinessoveragivenperiod.

Economistsabandonedexperiencedutilityearlyinthetwentiethcentury,infavourofanewinterpretation,inwhichutilityrepresentsÔwantabilityÕ(Fisher,1918).Aper-son’sdecisionutilitiesarerevealedbyherchoices.Ofcourse,thetwodefinitionshavethesameextensionifpeoplewantwhattheywilleventuallyenjoy–anassumptionthatisimplicitlyadoptedinmanyeconomicanalyses.Ifweassumethatindividualsarerational,fullyinformedandseektomaximiseutility,thenthechoicestheymakeare,bydefinition,thosethatmaximiseexpectedutility.Neoclassicalwelfareeconomicsrestsonaconceptofdecisionutilitythatiscleansedofanyreferencetohedonicexperienceandwhichassumesthatdecisionutilitycanbeinferredfromthepreferencesthatagentsrevealintheirmarketchoices.

Wheremarketsdonotexist,asinthevaluationofpublicgoodsorofstatesofpersonalhealth,economistshavedevelopedprocedurestomeasuredecisionutilitiesbyelicitinghypotheticalchoices.1Toelicittheutilitiesofstatesofhealth,economistsanddecisionanalystshavedevelopedmethodsthatrequirearespondenttostatethe

*ThisarticlewasdevelopedwhenPaulDolanwasaVisitingResearchScholarattheCenterforHealthandWell-being,PrincetonUniversity,andwethanktheCenterforprovidingsupport.WearealsogratefulforthemanyhelpfulcommentsprovidedbyparticipantsatseminarsatHarvardUniversity,BostonUniversity,UniversityofMichigan,UniversityofMadison-Wisconsin,UniversityofChicago,UniversityofNorthCarolinaandtheMedicalUniversityofSouthCarolina.1Thecontingentvaluationmethodisfrequentlyusedtomeasurethevalueofpublicgoods,inthecontextsofenvironmentallitigationorcost-benefitanalysis.Thismethodinvolvessurveysinwhichrespondentsareaskedtostatetheirwillingnesstopayforagivenbenefit,suchasahypotheticalimprovementintheirhealth,orthecontinuedexistenceofaspeciesofbirds.

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probabilitymixoffullhealthanddeaththatmakesthemindifferentbetweenthatgambleandthecertaintyofanintermediatehealthstate–thestandardgamble(SG)method–orelserequiresthemtostatethelengthoftimeinfullhealththattheyconsidertobeequivalenttoalongerperiodoftimeinpoorhealth–thetimetrade-off(TTO)method(Dolan,2000;Byrneetal.,2005).2Theunitofthescaleisaquality-adjustedlifeyear(QALY),whichÔassignstoeachperiodoftimeaweight,rangingfrom0to1,correspondingtothehealth-relatedquality-of-lifeduringthatperiod,whereaweightof1correspondstooptimalhealth,andaweightof0correspondstoahealthstatejudgedtobeequivalenttodeathÕ(WeinsteinandStason,1977).SomehealthsystemsarenowusingQALYstohelpdetermineprioritiesintheallocationofresources.3Themaingoalofthisarticleistoquestionthevalidityofmeasuresofdecisionutilityfortheevaluationoftheweightsassignedtodifferenthealthstates,althoughourcritiqueappliestoanyrevealedorstatedpreferencemethoddesignedtoelicitvaluesfornon-marketgoodsfromrealorhypotheticalchoices.4Themethodsusedtoelicitweightsexpresswhatrespondentswantatthetimeoftheassessmentinrelationtofutureprofilesofhealththatdifferintheirqualityoflifeandriskofdeathorlengthoflife.Assuch,theyareunlikelytomeasuretheutilitycorrespondingtohealthÔduringthatperiodÕ.However,thechoicesthatrespondentsmakeinSGorTTOquestionsshould,tosomegreatextent,beguidedbyaccurateassessmentsoftheutilitycorres-pondingtothehealthstateinquestionoverthespecifiedperiod;seeKahneman(1997)foradiscussionofthisrequirementmoregenerally.ThefocusofourcritiqueofQALYsbasedondecisionutilitiesisthattherearegoodreasonstosupposethatthisrequirementwillnotbesatisfied.

InSection1,wediscusssomeoftheevidencepertainingtotheexperiencedutilitythatflowsfromdifferenthealthstatesandotherimportantfactors,which,onthewhole,suggeststhatpeoplequicklyadapttomany,butnotall,states.BecauseQALYsareprincipallydesignedtoinformresourceallocationinhealthcare,weconsiderinSection2someofthenormativeissuessurroundingtheroleofadaptationinthecontextofallocatingpublicresources.Allelseequal,ifadaptationtooneconditionismorecompletethantoanother,thentheformerwillbegivenlessprioritythanthelatter.Whilstwemayneedtobecautiousaboutusingadaptedpreferencesinsomecontexts,theproblemsassociatedwithallowingforadaptedpreferenceshavebeenoverstated,especiallywhendecidinghowtoallocateresourcesoncethebudgetforhealthcarehasbeendetermined.

Athirdmethod,thevisualanaloguescale,whichrequiresrespondentstoratehealthstatesonascalewithdefinedendpoints,suchas0fordeadand100forfullhealth,hasalsobeenusedbutitisnotfavouredbymosteconomistsanddecisionanalystsinvolvedinmedicaldecisionmakingbecauseitdoesnotrequiretherespondenttomakeachoice.3Forexample,theNationalInstituteforHealthandClinicalExcellence(NICE),whichoffersguidanceontheuseofnewandexistingmedicinesandtreatmentswithintheNationalHealthServiceinEnglandandWales,ismuchlesslikelytorecommendthataninterventionshouldreceivegovernmentreimbursementifthecost-per-QALYofthatinterventionishighascomparedtoifitislow.Whilstnoexplicitthresholdexists,aruleofthumbhasdeveloped,whichsuggeststhatinterventionsthatcostlessthan£30,000perQALYwillberecommendedforfunding,whilstthosethatcostmorethanthiswillnotberecommendedor,ifthecost-per-QALYisexpectedtofallovertime,willberecommendedforfundingasÔexperimentaltreatmentsÕ.4Ourcritiqueisfocusedontheuseofmeasuresofdecisionutilitytoelicitvaluesofthiskind,ratherthantheirusefulnessinothercontexts,suchaspredictingbehaviour.ÓTheAuthor(s).JournalcompilationÓRoyalEconomicSociety2008

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ForecastsoffutureutilityshouldthereforetakedueaccountofadaptationbuttheevidencewepresentinSection3suggeststhattheintuitiveforecastsoflaypeoplegenerallyfailtodoso.InSection4,wediscusstheresultsfromhealthstatevaluationstudies,whichareconsistentwiththeideathatpeopleunderestimatetheextenttowhichtheyandotherswilladapttochangedcircumstances.Inparticular,weconsiderhowthoseaskedtoimaginewhatitwouldbeliketobeincertainhealthstates(ÔthepublicÕ)havetheirattentiondrawnawayfromthepossibilityofadaptationandinsteadtowardstransitionalchangesinthehealthdomainalone,andtowardstheirimmediateaffectiveresponsetothehealthstateinquestion.

Theseconsiderationsmightleadonetoconcludethatdecisionutilitiesshouldbeelicitedfromthosewithdirectexperienceofthehealthstatesinquestion(ÔpatientsÕ).However,decisionutilitieswillalwaysreflectthefocusoftherespondent’sattentionatthetimeoftheassessment,ratherthanwhattheywillattendtowhileexperiencingaparticularhealthstate.PatientsÕdecisionutilitiesmaybefreeofsomeofthebiasesassociatedwithpublicvaluesbuttheydonottakedueaccountofanylossesassociatedwithadaptationthatmayhavealreadytakenplace.Whilstthepublicmayoverestimatethelossesassociatedwithagivenstateofhealth,patientsmayunderestimatesuchlossesand,importantlyinapolicycontext,therelativerankingofdifferenthealthstatesmaywellvaryfromoneanother–andfromtherankingsimpliedbyexperiencedutility.Patientscouldbeaskedtoconsidertheirpreviousexperienceswhenmakinghypo-theticalchoicesaboutthefuturebutthereisalsoevidencethatpeoplearenotverymuchbetteratrememberingtheimpactofpastexperiencesthantheyareatpredictingtheimpactoffutureexperiences.

Againstthisbackground,weareratherpessimisticabouttheuseofdecisionutilitytogenerateQALYs,althoughourcritiqueofdecisionutilitymaypromptotherswhoaremoresympathetictothisinterpretationofutilitytorefineanddevelopthemethodsofpreferenceelicitation.InSection5,wearguethatmoreelaboratestudiesdesignedtoelicitdecisionutilitiescannotovercomethefundamentalproblemwithsuchutilities,whichisthattheydonotaccuratelyrepresenttheutilitystreamsassociatedwithdifferenthealthstates.Wethereforesuggestthateconomistsshouldinsteadlooktowardsdevelopingmeasuresthatfocusmoredirectlyonexperiencedutility,andweprovidesomesuggestionsabouthowthismightbedone.Ourrecommendations,whichinvolveelicitingproxyvaluesforutilityasitisexpe-riencedmoment-to-moment,willalsoprovideeconomistsinvolvedinestimatingthewelfareeffectsofnon-marketgoodsbesideshealthwithanalternativetoexistingrevealedandstatedpreferencemethods.InSection6,weprovidesomeconcludingremarks.

1.ExperiencedUtility

Muchoftheevidenceontheimpactofarangeoffactorsonutilitycanbesummedupinoneword–adaptation.Adaptation–theprocessofadjustmenttoneworchangedcircumstances–occursatdifferentlevelsandindifferentways,rangingfrommolecularchangesatthecellularlevelthatdiminishtheperceivedorexperi-encedintensityofanobjectivestimulus(suchasmovingfromlighttodark)toovertbehaviourthatreducesexposuretothestimulus.Hedonicadaptationoccurswhen

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thereisaÔreductionintheaffectiveintensityoffavourableandunfavourablecir-cumstancesÕ(FrederickandLoewenstein,1999).Suchadaptationincludesbothsensoryadaptatione.g.adjustingtoanunpleasantsmellandcognitiveadaptatione.g.changesininterests,goals,values,or–importantlyformuchofthediscussionthatfollows–redeploymentofattention.

Inawidelycitedstudy,Brickmanetal.(1978)foundthataccidentvictimswhosustainedparaplegiaorquadriplegiainthelastyearreportedhappinesslevelsthatwere,onaverage,closertothoseofacontrolgroupthanmighthavebeenexpected(2.96ona0–5scaleforparaplegicsascomparedto3.82forcontrols).SchulzandDecker(1985)foundthatreportedhappinesslevelsofagroupofmiddle-agedandelderlyparaplegicsandquadriplegicswereonlyslightlylowerthanpopulationmeansofnon-disabledpeopleofasimilarage.Similarly,WortmanandSilver(1987)foundthatquadriplegicsreportednogreaterfrequencyofnegativefeelingsthancontrols.

Tyc(1992)foundnodifferenceinqualityoflifeorpsychiatricsymptomatologyinpatientswhohadlostlimbstocancerascomparedtoacontrolgroup.Inareviewofstudiesexaminingadaptationtoburninjuries,Pattersonetal.(1993)foundhighlevelsofpsychosocialadaptationbyoneyearafteraccident.Morerecently,Wu(2001)foundthatthosewhohavehadaheartconditioninthepastarelesslikelytoreportworseself-assessedhealthandemotionalhealthduetotheonsetofnewconditionthanthosewhohavenotpreviouslyhadexposuretohearttrouble,which,itisclaimed,isÔquitesup-portiveofthetheoryofhedonicadaptationÕ.

Whilstadaptationtochangedhealthappearswidespread,itiscertainlynotuni-versal.Thereis,forinstance,evidenceofincreasedsensitisationtopain(Thompsonetal.,1973).Inadiarystudyoverfourweeksof80patientswithunexplainedpain,Petersetal.(2000)foundthatpatientswithlessthansixmonthsofpainreportedsignificantlylesspainintensity,disabilityandfatiguethanpatientswhosepainhadpersistedformorethansixmonths.Moreover,thereisalsoevidencethatcopingwithrepeatedepisodesofpainleavespatientsmorevulnerabletostressfulevents(Lennonetal.,1990).Thereissomeevidencethatpeopledonotadapttopro-gressivediseases–seeLivnehandAntonak(1994)indegenerativedisordersandAntonakandLivneh(1995)inmultiplesclerosis–butinterpretingtheseresultsisproblematicbecausethehealthstatesassociatedwithsuchconditionsareconstantlychangingand,therefore,thehedonicstatecouldbedeterioratingataslowerratethanthecondition,whichwouldstillbeconsistentwithadaptiveprocesses(FrederickandLoewenstein,1999).Thereisgenerallytheneedformorelongitudinalstudiesthatcontrolfortheeffectsofconfoundingvariables.

Itcouldalsobethatsomeoftheseresultsareexplainedbyresponseshift(SprangersandSchwartz,1999).Paraplegics,forexample,mightcomparetheirhappinesstootherparaplegics,elevatetheircurrentratingstoreflectthecontrastwiththeextremedespairimmediatelyfollowingtheonsetofdisability,oradoptlowerstandardsfortheintensityofpositiveaffect,allofwhichwouldleadtooverinterpretationofthedegreeofadaptation.Aspossibleevidenceofthis,intheBrickmanetal.(1978)study,theaccidentvictimsrememberedtheirhappinessashavingbeenmuchhigherinthepastthandidthecontrols(4.41ascomparedto3.32,respectively).Similarly,PostulartandAdang(2000)showthatkidney-pancreas

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transplantpatientsremembertheirpre-transplantqualityoflifetobelowerthantheyreportedatthetime.5However,itisalsoentirelypossibletheparaplegicsetc.,whenaskedtoimaginetheirlifebeforeanadversechangeintheirhealth,mayfocusonthosethingsthatmadetheirlifedifferenttonowratherthanonthosemanythingsthathavebeenunaffectedbyparaplegiaetc.Andwhilstresponseshiftmakesintertemporalandinterpersonalcomparisonsofself-reportsproblematic,itcannotexplainallchangesinpreferencesthattakeplace.Forexample,thereisstrongevidenceofadaptationevenwhenphys-iologicalorbehaviouralmeasuresareused,bothofwhichshouldbelesspronetoresponseshift:Krupat(1974)foundthatthatpriorexposuretothreatreducedgalvanicskinconductance(aphysiologicalmeasureofthreat);andDaretal.(1995)foundthatwarveteranswithmoreseverepastinjuriescouldholdtheirfingerinhotwaterforlongerbeforeclassifyingitaspainfulthanveteranswithlessseverepastinjuries.

ThereisnowevidencetoshowthatindividualsÕlifesatisfactionadaptstochangesinanumberofotherfactorsandlifeevents.Thereisasmallpositiverelationshipbetweenincomeandhappinessincross-sectionalanalysesbutvirtuallynorelationshipatallintime-seriesanalyses(Easterlin,2001).6ThereisevidencethattheincomeanindividualconsiderstobeÔsufficientÕisprimarilydeterminedbyhercurrentincome(vanPraagandFerrer-i-Carbonell,2004),andthatadaptationappearstooffsetabouttwo-thirdsofthebenefitsofanyincreaseinincome(FreyandStutzer,2002).Usingdatafroma15-yearstudyofover24,000Germans,Lucasetal.(2003)showthat,onaverage,peopleexperienceanincreaseinhappinessintheyearssurroundingmarriagebutafterthesecondyearofmarriagetheyappeartoreturntotheirbaseline.Eveninthecaseofwidowhood,adaptationisclosetocompleteafterabouteightyears.Thesedataaregenerallysupportiveoftheideathatpeopleareonahedonictreadmill(BrickmanandCampbell,1971).However,itisworthnotingthattheaverageresultsmasksomeimportantindividualdifferences.Inparticular,thosewhoreactedstrongly(eitherpositivelyornegatively)werestillfarfrombaselinelevelsyearsaftertheevent.

ThesameGermandataalsohighlightthepointthatadaptationisnotfoundforallconditions.Inthecaseofunemployment,forexample,averagelifesatisfactionfallsfromaround7.2onascalefrom1–10tothe6.3inthefirstyearandisstillonly6.5inthefourthyearofunemployment(Clarketal.,2004).Thereisalsoevidencetosuggestthatpeopledonotadapttonoisethatispoorlyunderstoodorunpredictableinitstiming.7Inastudyoffirstyearcollegestudents,Weinstein(1978)foundthatannoyancewith

Tooffsetproblemswithresponseshiftpartially,respondentsarenowsometimesaskedtorateastan-dardisedvignettealongsideratingsofsatisfactionwithownhealth,sothatthelattercanberecalibratedagainsttheformer(Salomonetal.,2004).Suchanapproachservestoincreasetheagegradientinself-reportedhealth;thatis,self-reportedhealthdeclinesmorerapidlywithageonceeachindividual’shealthratinghasbeenrecalibratedagainsthis/herratingofthevignette.6Whilstthereareotherpossibleexplanationsforthisapparentparadox(i.e.somerelationshipbetweenincomeandlifesatisfactionatonepointintimeandnorelationshipovertime),itislikelythathedonicadaptationisplayingabigpart.OneotherpossibleexplanationisthattheriseinincomeovertimehasbroughtwithiteconomicÔbadsÕ(suchasgreaterincomeinequality,risingcrimeandhigherdivorcerates),whichoffsetanyincreaseinlifesatisfactionfromanincreaseinincome.7Whennoiseispredictable,hasbeenheardmanytimesbefore,changeslittlefromonetimetothenext,andiseasilyassimilatedtopeople’spriorschemas(e.g.thesoundofaclockticking),thereislikelytobeadaptation;seeWilsonandGilbert(2005),andhowthisevidenceisconsistentwiththeirAREAmodelofemotionaladaptationinwhichpeopleattendtonovelevents,reacttothoseevents,explaintheevents,andasaresultadapttothem.

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noiseincollegeincreased.Thesameauthoralsoobservedincreasingpessimismaboutadaptationtohighwaynoise:afterfourmonths,underone-thirdspontaneouslymen-tionednoiseassomethingtheydislikedintheneighbourhood,whereasoveronehalfdidafter16months(Weinstein,1982).

2.AdaptationinaPolicyContext

Itwouldseemthatadaptationtomany–butnotall–conditionsiswidespread.Thefactthatpeople’spreferencesundergosomeformoftransformationinaprocessofadaptationwouldnot,normally,beregardedasanymoresignificantthanthechangestopreferencesovertimethatmayoccurbecauseofalltheotherexperiencesthattheyencounter.Butinthecontextofresourceallocation,adaptationraisesanormativeproblembecause,allelseequal,themoreapatientadaptstohercondition,thelesspriorityshewillreceiveinthecompetitionforresourcesthatimprovequalityoflife.Intheextremecase,wherethereiscompleteadaptationtoahealthstate(suchthatitgetsaquality-adjustmentweightof1.0),therecanbenoincreaseinutilityfromitstreat-mentorcure.8Theextenttowhichgivinglowerprioritytothosewhohaveadaptedmostisunjustwilldependlargelyonelementsoftheadaptationprocess;seeMenzeletal.(2003)foradetaileddiscussion.Sen(1992)hasdiscussedoneparticularlyregrettableelementofadaptation;namely,entrencheddeprivation.Inhiscritiqueofutilitarianism,heclaimsthatÔdesirefulfilmentÕisÔneglectfuloftheclaimsofthosewhoaretoosubduedorbrokentohavethecouragetodesiremuch...Insituationsoflong-standingdepriva-tion,thevictimsdonotgoongrievingandlamentingallthetime...Theextentofaperson’sdeprivation,then,maynotatallshowupinthemetricofdesirefulfilment...ÕHowever,Senisconcernedwithaspecialcase.PeoplewhoadapttochangedhealthstatusarenotgenerallyÔsubduedorbrokenÕ,andtheirtastesandpreferencesshouldnotbeignored.WhilstSen’sargumentforcesustopauseabouttooreadilyusingadaptedutilities,itdoesnotjustifyarejectionofvaluesshapedbyadaptation.

Theuseofadaptedvaluesraisesarealdilemmawhenpatientssuccessfullyadjusttheiractivitiesortheirgoalsinlinewiththeirchangedcircumstances(Menzeletal.,2003).Paraplegics,forexample,maytakeupaerobicwheelchairingiftheystilldesirephysicalexerciseortheymaydevelopaninterestinmusictoreplaceapreviousinterestinphys-icalactivity.Inlightofsuchlaudableeffortandachievement,itmaybeconsideredunjusttowithholdtreatmentfromparaplegicsonthegroundsthatthepotentialforgainsinexperiencedutilityarelimited.However,ifthisargumentisaccepted,thenanadvantagegetscreatedforthosewhohaveadapted.Treatmentsforsuchpeoplewillgetgreaterprioritythanarewarrantedbythesizeoftheactualutilitygainfromthem.ResourceallocationdecisionswillthenbemadeasifadaptedpatientsÕgainsinexperiencedutilitycountformorethanthegainsofpatientswhoadaptless.Thisalsoseemsunfair.

Theoppositeistrue,ofcourse,forlife-savingorlife-extendinginterventions,wherecompleteadaptationtoahealthstatewouldmeanthatthenumberofQALYsgainedfromsavingsomeone’slifeinthatstatewould,allelseequal,bethesameasthenumberofQALYsgainedfromsavingthelifeofsomeoneinfullhealth.TheincreasedprioritygiventoadaptedpatientsthatcomesfromtheuseofÔadaptedutilitiesÕinlife-extendingcontextsisoftenignoredbythosewhoargueagainsttheuseofsuchutilitiesbutitisinthecontextoflife-enhancingtreatmentsthattheissueofadaptationpresentsuswithapotentialproblem.ÓTheAuthor(s).JournalcompilationÓRoyalEconomicSociety2008

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HereinliesaÔvexingmoralproblemÕ(Murray,1996)thatwecannothopetoresolvehere.But,ingeneral,itseemsentirelyappropriatetogivegreaterprioritytothosestatesthatpeopledonotadapttooverthosethattheydoadaptto.Thiswouldseemtobeparticularlytruewhenallocatingresourcesamongstpatientsoncethebudgetforhealthcarehasbeendeterminedi.e.oncewehavedecidedthepriorityaffordedtopatientsinrelationtoothergroups.Giventhis,weneedtoconsiderhowwellpeoplepredictchanges–includinganyadaptation–intheirfuturepreferences.

3.PredictionsAboutExperiencedUtility

Howaccuratelydopeoplepredicttheirfutureutilityandhowwelldotheypredictadaptationthatisrelevantforresourceallocation?Theevidenceonthesequestionscomesfromvarioussourcesanditisnotveryencouraging.Forexample,Sieffetal.(1999)askedpeopletestingforHIVtoratethedegreetowhichtheyagreedordis-agreedwithanumberofitemsaboutaffecte.g.ÔIfeelangrymostofthetimeÕ.Theresponseswerestandardisedona0–100scale,where100representscompletedistress.Theanticipateddistressfromapositivescorewas95,whereastheactualdistresswas78.Theanticipateddistressfromapositivescorewas49,whereastheactualdistresswas55.Smithetal.(2006)reportdatafromcolostomypatients,halfofwhomhadtheircolostomiesreversedatsomepoint.Thecurrentqualityofliferatingona0–100scaledidnotdifferbetweenthesetwogroups(71forformerpatients,comparedto67forcurrentpatients)butthecurrentpatientspredictedthattheirqualityoflifewithnocolostomywouldbe83i.e.12pointshigherthanwhatwasactuallyreportedbytheformerpatients.Itis,however,difficulttodeterminewhetherthesedifferences,whicharestatisticallysignificant,aresignificantinaÔutilitylossÕsense,andbettermethodsofmeasuringexperiencedutilityarerequiredbeforewecouldmakethisclaim(seeSection5below).

AstudyoflaryngealcancerpatientsprovidesevidencethatthedecisionutilitiesattachedtoÔendoftherapyÕhealthstates(asmeasuredusingtheTTOmethod)aresimilarinanticipationofthosestatesandwhentheyareexperienced(Llewellyn-Tho-masetal.,1993).However,thetimeintervalbetweenevaluationswasonlyninedaysanditispossiblethatsomerespondentsrememberedtheirearliervaluations.Importantly,thereweresignificantdifferencesintheexpecteddirectionforthosereportingthemostsevereendoftherapystates.Itisnowwidelyrecognisedthatitischangesinstates,ratherthanthestatesthemselves,thatarethecarriersofutility(KahnemanandTversky,1979),andtheresultshereareconsistentwiththeideathatpeopleareabletopredicttheiremotionalresponsetosuchchangeswithafairdegreeofaccuracy,atleastovertheveryshortterm.

Instudiesoutsideofhealth,itseemsthatpeoplegenerallyfailtorecognisetheimportanceofarangeofadaptationprocesses,expectingbothgoodandbadfeelingstolastalotlongerthantheyreallydo.Forexample,Gilbertetal.(2002a)askedvotersinTexasduringthe1990electionforgovernor(whichwaswonbyGeorgeW.Bush)howtheywouldfeelonemonthaftertheelectioniftheircandidatehadlost.Respondentsexpectedtofeelmiserablebutwhenaskedhowtheyfeltonemonthlater,peoplewerejustashappywhethertheircandidatehadwonorlost.Theseandotherresultssuggestthat,whilstpeoplecangenerallypredictthevalenceandtypeofemotion

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fromeventsreasonablywell,theyoverestimatetheintensityandespeciallythedurationoftheirreactionstothoseevents(WilsonandGilbert,2003).

OneimportantreasonforthisisthatwefailtoappreciateourabilitytoÔmakesenseÕofthethingsthathappentous(WilsonandGilbert,2003).9Inrelationtoadaptationtonegativeevents,suchasadversechangesinhealth,WilsonandGilbert(2003)suggestthatwefailtoappreciatethepowerofourpsychologicalimmunesystem(PIS),whichdetectsandneutraliseseventsthatchallengeoursenseofwell-being.Ofcourse,someadverseevents,likeparaplegia,mayresultinpermanentlossesinwell-beingbutthoselosseswouldbealotworseifwedidnotpossesspsychologicaldefencesthathastenourrecoveryfromthem.AswithÔsensemakingÕmoregenerally,thePISfunctionslargelyoutsideofconsciousawarenessandismoreeffectivebyoperatingÔbehindthescenesÕ.Itislittlewonder,then,thatwefailtoanticipateit.

Inastudyoflaypredictionsofadaptation,Cohn(1999)–seeKahneman(2000)–asked362respondentstoevaluatethewell-beingoffictitiousmembersofvariouscat-egoriesofpeople,includinglotterywinnersandparaplegics.Halfoftherespondentsweretoldthattheevent(winningthelottery,becomingparaplegic)hadoccurredonemonthbefore,andtheotherhalfweretoldthateventhadoccurredoneyearbefore.Respondentswerealsoaskedtoindicatewhethertheypersonallyknewalotterywinneroraparaplegic.Thosewhodidnotknowalotterywinneroraparaplegicwerelargelyinsensitivetothetimevariable.Thosewhoknewalotterywinnerorparaplegic,how-ever,weremuchmoresensitivetothetimecourseoftheevent:thebetween-groupscomparisonshowedthattheserespondentscorrectlypredictedthatlotterywinnerswouldbecomelesshappyandparaplegicslessmiserableovertime.Thetwogroupsdidnotdiffersignificantlyintheirjudgmentsofwell-beingonemonthaftertheevent,whichsupportstheideathatpeoplearebetterabletopredictinitialchangesinutility.

4.DecisionUtilitiesinHealth

Overthelastthirtyyearsorso,utilitiesformanydifferentstatesofhealthhavebeenelicitedfrompatientsandthepublic.10Consistentwiththeevidencepresentedabove,thereisnowplentyofevidencetosuggestthatmembersofthegeneralpublicover-estimatethelosses(andunderestimatetheadaptation)associatedwitharangeofhealthstates.Inthefirstempiricalstudyonthisissue,SackettandTorrance(1978)askedthepublicandhomedialysispatientstovaluearemaininglifetimewithchronicdialysisusingtheTTOmethod.Theaverageutilityfromthegeneralpublicwas0.39,ascomparedto0.56fromdialysispatients.Ifitwerepossibletoreturndialysispatientstofullhealth,thenthegainwouldbe0.61QALYsperyear(1.0–0.39)ifweusedpublicutilitiesand0.44ifweusedpatientutilities.Inthiscase,usingpublicvalueswouldreducethecost-per-QALYoforgantransplantationbynearly40%.

FrederickandLoewenstein(1999)notethepossibilitythatbothadaptationandsense-makingcouldbespuriouslycorrelatedthroughtheircommonrelationtoathirdfactor,suchasinnatehappiness,whichcausespeopletobothadjustsuccessfullytotheirnewconditionandtomakesenseofit.However,thisislessplausibleinlightofstudiesbyWilsonetal.(2005),whichmanipulatedtheeaseofsensemakingandfoundthattheharderitwastomakesenseofagoodevent,thelongertheaffectivereactionlasted.10Thegeneralpublicis,ofcourse,aheterogeneousgroupintermsofitshealthandwillcontainmanypeoplewhosehealthisverypoorbut,onaverage,thegeneralpublicareinbetterhealthstatesthantheonestheyareaskedtoimagineexperiencinginmostvaluationstudies.ÓTheAuthor(s).JournalcompilationÓRoyalEconomicSociety2008

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Sincethen,whilstsomestudieshavefoundlittledifferenceinpublicandpatientvaluations,mosthaveproducedsimilarresultstothosefoundbySackettandTorrance,withsimilarlyimportantimplicationsfortheresultsfromcost-per-QALYratios.11Inareviewof39studies,includingtheirown,deWitetal.(2000)foundthat23studiesreportpatientvaluestobehigherthanpublicones,2reportpublicvaluestobehigher,11reportnodifferenceand3reportcontradictoryfindings.Itisnotclearwhytherearedifferencesacrossstudies,althoughthesmallsamplesinsomeofthestudiesmighthelptoexplainwhysomeofthemreportnodifferences.Interestingly,thetwostudieswherepatientvaluesareactuallylowerthanpubliconesareinsamplesofmenopausalwomenandwomeninchildbirth.

4.1.UtilitiesfromthePublic

Thereareatleastthreeotherfactorsthattendtoreducethepublic’sassessmentsofhealthstatesthataredifferenttotheirown,allofwhichdrawrespondentsÕattentionawayfromthepossibilityofadaptation.First,attentionisdrawntothetransitionfromonehealthstatetoanotherandthetransitorychangeinwell-beingthatwillresult.So,whenpeopleareaskedtovalueparaplegia,theywilltendtofocusonbecomingaparaplegic,whichwillinitiallybethefocusofmuchattention–theywillbeaparaplegicÔfull-timeÕ–andhencethesourceofmuchmisery.Butafterthistransitionalperiod,aparaplegicwillonlybeaparaplegicÔpart-timeÕ,astheyattendtootherthingsintheirlifethatareunaffectedbytheirparaplegia.SovaluationsarelikelytobeaffectedbyaÔPeak-StartRuleÕ(DolanandWhite,2006),whererespondentsfocusonthepeaklossandtheimmediateloss(whichinmostcasesarelikelytooccuratthesametime).Thisisalsoconsistentwiththeideathatchangesinstatesaretherealcarriersofutility(KahnemanandTversky,1979).

Second,andevenallowingforthetransitionphase,attentionisfocusedonthehealthdomainratherthanonotherdomains(suchaspersonalrelationships)whichmaybeunaffected,orevenenhanced,bychangedhealthstatus.Healthstatesaretypicallydescribedusingonlyalimitednumberofdimensionsandalwaysinwaysthatdrawstherespondent’sattentiontothosedimensionsthatwillbeadverselyaffected.Butoneofthewaysinwhichweadapttochangedcircumstancesisbyredeployingourattention.So,ifadaptationtoparaplegiatakestheformofnotthinkingaboutit(butratherthinkingaboutdomainsoflifeotherthanhealth),thiswillnotbepartofthewayanyonethinksaboutparaplegiainadvanceoftheevent.

Third,itispossiblethatSGandTTOresponsesreflectimmediateaffectivereactionstothehealthstateinquestion(Wilsonetal.,2002),whichinthecaseofsomeseverehealthstatesislikelytobeaninitialshockreactionto,orfearassociatedwith,thatstate.So,notonlymightrespondentsbechannelledtoconsideralimitednumberof(pos-siblyrelativelyunimportant)aspectsofthefuture,theymightevenbechannelledawayfromthinkingaboutthefutureatallandtowardsfocusingoncurrentfeelings.From

Thereisthepossibilitythatsomeoftheseresultscouldbeexplainedbyresponseshift(Ubeletal.,2003).However,Baronetal.(2003)foundthatmakingtheresponsescalesmoreprecisewithwell-defineddemar-cationsservedonlytoincreasethediscrepancybetweenthevaluesofpatientsandthepublic.ÓTheAuthor(s).JournalcompilationÓRoyalEconomicSociety2008

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thisperspective,theapparentfailuretotakeaccountofadaptationisaproductofthewayinwhichcurrentemotionsintrudeonassessmentsofthefuture,aswellasanyadditionalfailuretofullyconsiderthatfuture.12Ofcourse,policymakersmaywishtodevoteresourcestothehealthstatesthatpeoplefearthemost.Fearhasaveryrealeffectonanindividual’sutilityandonherbehaviour,includingherconsumption.Insofarasfearssurroundingparticularhealthstatescanbereducedbyexpenditureonthetreatmentandpreventionofthosestates,policymakersmaybeabletoincreaseutilitybysuchexpenditures(DolanandWhite,2006).Moreover,thepublic,throughthedemocraticprocessorpressuregroups,maydemandthatcertainhealthstates,suchasthoseassociatedwithcertainkindsofcancer,begivengreaterpriority.However,accountingforfearisaquiteseparateissuefromaccountingforthelossesinutilityfromagivenhealthstate,andSGandTTOutilitiesconflatefearsthatpeoplehaveaboutexperiencingpoorhealthwiththeirassessmentsofhowtheirliveswillbeaffectedbypoorhealth.13Inanyevent,weareunawareofanyeconomistsarguingfortheSGorTTOonthegroundsthattheypickuppeople’slegitimateaffectiveresponsestothehealthstatesinquestion.Indeed,economistshavedescribedhealthintermsofdimensionsofhealth(mobilityetc.)ratherthanintermsofconditions,likecancer,inordertoavoidintroducingtoomuchemotionintotheresponses.TheSGandTTOareassumedtotapintopeople’scognitiveassessmentsoftheutilityassociatedwiththosestates,despitethelackofanyevidencetosupportsuchanassumption.Respondentsthemselvesmaythinkthattheyaregivingaconsideredresponsetotheutilityassessmentquestionbutmayinfactbeusingtheirimmediatefearofthehealthstateasaproxyfortheirfutureassessmentofit(GilbertandWilson,2000).

FocusingrespondentsÕattentiononthetransitionfromonestatetoanother,emphasisingthenegativeconsequencesforhealth,andpickingupsomeaffectiveresponsetothechangeinhealth,maytogetherexplainwhymanystatesareconsideredtobeworsethandeathinthosestudiesthatarebeingusedtocalculateQALYsforuseinpolicysettings.14Moreover,notonlydoesitappearthatrespondentsfailtoantici-patehowtheywilleventuallyadapttomanyadversehealthstates,itseemsthattheythinkmanystateswillgetworsethelongertheylast.Forexample,BleichrodtandJohannesson(1997)foundthatSGvaluesforstateslastingtenyearswerehigherthanwhenthesamestateslastedfor30yearsandSackettandTorrancefoundthatTTOvaluesdeclinedoverdurationsofthreemonths,eightyears,andtheremaininglifeexpectancyoftherespondent.Insomecases,ahealthstatethatisconsideredtobe

Aclassicexampleofthewaycurrentfeelingsaffectdecisionsaboutthefutureisshoppingatthesupermarketwhenhungry:whenpeoplearehungry,theytendtoshopasistheyexpecttoremainperma-nentlyhungry,butshopperswhoaregivenamuffintoeatbeforeenteringtheshoparemorelikelytolimittheirpurchasestothoseitemsontheirshoppinglist(Gilbertetal.,2002b).13Foradiscussionoftheroleoffearassessmentinthecontextofeconomicevaluation,seeAdler(2004),andforarelateddiscussioninthecontextofimaginedrisks,seeSunstein(2002).14Forexample,theEQ-5D,whichisusedwidelyinevaluativestudies,generates243possiblestatesofhealth(fivedimensionsofhealth,eachwiththreelevelsofseverity)andone-thirdoftheseare,onaverage,consideredtobeworsethandeadbyaUKgeneralpopulationsamplethatvaluedthesestatesusingtheTTOmethod(Dolan,1997).

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betterthandeadforashorterdurationisseenasbeingworsethandeadwhenitlastsforlonger(DolanandStalmeier,2003).154.2.UtilitiesfromPatients

ElicitingSGandTTOutilitiesfromthosecurrentlyexperiencingthehealthstateinquestionwillavoidsomeoftheproblemsassociatedwithelicitingutilitiesforhypo-theticalstatesfromthepublic.However,thefundamentalproblemwithutilitieselicitedinadecisioncontextremains;namely,thattheresponseswillreflectwhatevertherespondent’sattentionisdrawntoatthetimeoftheassessmentratherthanwhatitwillbedrawntoinfutureexperiences.Patientsmaywellhaveexperienceofthestatetheyarebeingaskedtovaluebuttheycanbeexpectedtoconsideronlyalimitedsub-setofpossiblefutureexperiencesintheutilityelicitationtask.

Inaddition,theSGandTTOmethodsbothrequirepatientstoconsiderhowtheirfutureexperienceswouldbedifferentweretheytobeinfullhealth.Whilstmanypatientswouldhavehadpreviousexperienceoffullhealth,theirrecollectionofthis–atleastinanevaluativesense–maybefarfromperfect(seebelow)andtheyareagainlikelytofocusononlyalimitednumberofwaysinwhichtheirliveswouldbedifferentfromnow.Differentpatientsmayfocusondifferentaspectsoftheirfuturelivesandmayhaveverydifferentconstructionsofwhatfullhealthwouldmeantothem,andthesedifferentconceptualisationscouldgosomewaytowardsexplainingthewidevariationinutilitieselicitedfromreasonablyhomogeneousgroupsofpatients;seedeWitetal.(2000).

Moreover,tobeofuseinapolicysetting,decisionutilitiesfrompatientswillneedtoreflecthowbeinginthatstateimpactsontheaveragepatient’slife,asitwillbeexperiencedinthefuturebythatpatient.Mostpatientswillexperiencesomeinitialutilitylosseveniftheyfullyadapttotheirhealthstate.Adaptedpatientsdonothavetheirattentiondrawntohowthestateimpactedupontheminthepastandso,tofullycapturethis,decisionutilitieswouldneedtobeelicitedfrompatientsateverystageofthecondition’sprogression.16So,evenifpatientswereabletoforecastaccuratelyhowtheircurrenthealthwouldaffecttheminthefuture,theirdecisionutilitieswouldnotfullyreflecthowthatstatehadaffectedtheminthepast.

Itmightbepossibletoaskcurrentpatientstogivedueconsiderationtohowthestateimpactedupontheminthepastwhenconsideringtheirdecisionutilitiesaboutthefuture.Evenifpatientsreconstructthetimecourseoftheirconditionmoreorlessaccurately,17theirdecisionutilityforhealthwillbeaffectedbyhowtheyrecallthepreviouschangeintheirhealthchangingtheirlife.Patientsarelikelytousetheir

TheconditionsoflogicalrationalityrequiredbytheQALYmodelhavenotbeendiscussedinthisarticle,asanextensiveliteratureonthisissueexistsalready(TsuchiyaandDolan,2005)butevidencesuchasthisviolatestheassumptionthatthevalueofahealthstateisunaffectedbyitsduration.16Despitethefactthatadaptationtakestime,theliteraturehaslargelybeensilentontheissueofwhenintheadaptationprocesspreferencesshouldbeelicited(Dolan,1999andSharmaetal.,2004,representnotableexceptions).17Thereissomeevidencethatpatientshaveatendencytounderestimatethetrueincidenceofprevioussomaticsymptoms(SimonandGureje,1999)andtocombineseparateepisodesintoasingleone(Meansetal.,1989).

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currentpreferencestorationaliseapreviouschange(Wilsonetal.,2003),sotheymaywellrememberthetransitionintotheircurrenthealthstateasbeinglessintensethanitwasfelttobeatthetime.Aspossibleevidenceofthis,Barsky(2002)reportsonanumberofstudiesthatshowthatretrospectiverecallofhealthishighlycorrelatedwithindividualsÕcurrenthealthstateandnotsowellcorrelatedwiththeirinitialstate.Moregenerally,thereisnowplentyofevidencetosuggestthatourmemoriesdonotrecallpastutilitiesandtheirdurationparticularlywell.Forexample,RedelmeierandKahneman(1996)askedpatientsundergoingacolonoscopytoreporttheirlevelofpaineverysixtysecondsthroughouttheprocedureandtosubsequentlyratetheÔtotalamountofpainexperiencedÕonasimilarscale.ThecorrelationsbetweentheÔon-lineÕandglobalratingssuggestedthatrespondentsÕmemoriesoftheexperiencewereinfluencedprimarilybythemostpainfulmomentoftheprocedureandthelevelofpainattheveryendoftheprocedure:thedurationoftheprocedurewaslargelyignored.Therefore,itappearsthatpatientsuseaÔPeak-EndRuleÕ,whichignoresthefullsetofexperiencesandhowlongtheseexperienceslast(Kahnemanetal.,1997).4.3.IllustratingtheProblemwithDecisionUtilities

Givenallofthis,itisentirelypossiblethatdecisionutilitiesfromthepublicwillleadtoadifferentrankingofhealthstatestodecisionutilitiesfrompatientsandthatbothwillmisrepresenttheutilitylossassociatedwiththeexperienceofthosestates.Toseethis,andintheabsenceofanygooddataontheexperiencedutilityassociatedwiththechangingnatureofhealthconditionsovertime,considerFigure1.Thetwosolidlinesshowtheexperiencedlosses(fromfullhealthwithU¼1)overtime(fromT¼0)fortwohealthstates,AandB.StateAstartsoffasworsethanstateBbutthereismoreadaptationtoBthantoA.Assumingthatutilityisinterpersonallycomparableandcanbeexpressedonacardinalscale,byT¼1,thetotallossinexperiencedutilityisthesameforbothstates.18Letusassumethatrespondentsfromthegeneralpublicaccuratelyassesstheinitialutilitylossassociatedwitheachstatebutthattheyfailtoforecastanyadaptationovertime.TheutilitiestheygenerateforstatesAandBareshownbythedottedlineslabelledAGPandBGP.BecauseAstartsoffasworsethanB,AGPBP.

Inevaluatingtwointerventions,onewhichpreventedstateAandonewhichpre-ventedstateB,theformerwouldappeartopreventmoreQALYlossesiftheutilitiesofthepublicareusedandthelatterwouldappeartopreventmoreQALYlossesiftheutilitiesofpatientsareused.19Infact,thelossinexperiencedutilityandthetotalutilityfrombothstatesisidenticalovertheperiodT¼0toT¼1.Itisourcontentionthat,

ThestandardQALYmodelassumesthatutilitycanbecomparedacrosspeopleandtheSGandTTOmethodsbothassumethatutility(evenifitisrisk-adjustedortimediscounted)iscardinal;seeDolan(2000).19Inasimilarway,inevaluatingtwointerventionswhichwouldeitherleavepatientswhowouldotherwisedieinstateAorstateB,thelatterwouldgeneratemoreQALYSiftheutilitiesofthepublicareusedandtheformerwouldgeneratemoreQALYsiftheutilitiesofpatientsareused.ÓTheAuthor(s).JournalcompilationÓRoyalEconomicSociety2008

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U = 1T = 0T = 1APBPBGPAGPFig.1.LossesinExperiencedUtilityfromTwoHealthStates,AandB,andDifferencesinDecisionUtilitiesfromtheGeneralPublic(GP)andPatients(P)allelseequal,thesamepriorityshouldbeaccordedtothetreatmentandpreventionofstatesAandBoverthegivenperiod.Todootherwiseistodistortprioritiesinfavourofthosewhoadaptifpublicpreferencesareusedandagainstthosewhoadaptifpatientpreferencesareused.

5.MeasuringExperiencedUtility

Itmaybepossibletodevelopmoresophisticatedmeasuresofdecisionutilityandtoproviderespondentswithmoreinformationandcontextabouttheexperiencesasso-ciatedwiththestatestheyareaskedtovalue.Animportantadvanceinthisregardhasbeentheuseofvideosofrealpatientsoractorstopresentamorecompletepictureofwhatlifeinagivenhealthstatereallywouldbelike;see,forexample,Sloanetal.(1998)andLenertetal.(2005).However,decisionutilitieswillstillreflectwhattherespon-dent’sattentionisdrawntoatthetimeoftheassessment.Ubeletal.(2001)devisedanumberofnovelstudiesinwhichtheyattemptedtodrawrespondentsÕattentionawayfromthenegativeeffectsofdifferenthealthconditionsbyaskingthemtoconsiderhoweachconditionwouldaffectarangeofdifferentdomainsoflife,butthevaluationsrespondentsgavewerelargelyunchanged.20Manypeoplemayevenbeawareoftheirgeneralpropensitytomispredictfutureutility–andtheycancertainlybemadeawareinutilityassessmentstudies–buttheymaystillcontinuetomispredictitonacase-by-casebasis,inmuchthesamewayaspeoplecansimultaneouslybeawareoftheirgeneraltendencytoprocrastinateandstillprocrastinateonacase-by-casebasis(O’DonoghueandRabin,1999).

Inaddition,decisionutilitieswillneedtoconformtotheconditionsoflogicalrationalityrequiredbytheQALYmodel.Theseconditions,setwithinanexpectedutilityframework,requirethattheutilityofahealthstateisunaffectedbyhowlongthe

OnlyinoneoutoftenquestionnairevariantsdidrespondentsÕvaluationsofahypotheticalstate(suchasblindnessandparaplegia)increasewhentheywereaskedtothinktheimpactthestatewouldhaveonawiderangeoflifedomains.

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statelastsandunaffectedbythestatesthatcomebeforeorafterit.Generally,respondentsseehealthstatesasgettingworsethelongertheylastandadditivesepa-rabilitydoesnotholdeither,althoughtherearenoconsistentpatternsintheviolationsthatwouldallowasimplealgorithmtoadjusttheQALYmodeltobetterrepresentindividualpreferencesoverfuturehealthprospects(TsuchiyaandDolan,2005).EconomistshaverespondedtosuchevidencebyderivingQALYsusinggeneralisationsofexpectedutilitytheory,suchasrank-dependentexpectedutilityandprospecttheory(Doctoretal.,2004).SuchextensionstothestandardQALYmodelareverymuchinkeepingwiththeemphasisineconomicsanddecisionscienceonlogicalcriteriaofrationality,whichcanbeassessedentirelybyreferencetoasystemofpreferencesinwhichonlyinternalcoherencematters(Sen,1993)buttheydonotaddressthemoresubstantiverationalityrequirementthatindividualsshouldcorrectlypredicttheeffectsofchangesinhealthontheirpreferences.

So,ratherthan–oratleastaswellas–refiningthemethodsforelicitingdecisionutilities,wesuggestthateconomistsshouldlookformoredirectmeasuresoftheutilityassociatedwithdifferentstatesoftheworld.Economistsareshowingincreasinginterestintheuselifesatisfactionratingsasabasisforwelfareassessment(Ferrer-i-CarbonellandFrijters,2004),andtheimpactofdifferenthealthstatesisyettobefullyexploited.Insofarasthisworkconsiderssatisfactionaccordingtodomainsoflifesuchashealth,income,etc.,ithasmanyparallelstotherecommendationbyBroome(1993)thatweuseaÔdirectmethodÕ,ratherlikeavisualanaloguescalethatsimplyasksrespondentstoratetheÔgoodnessÕofahealthstate.Economists,whohavefocusedontheelicitationofdecisionutilitieselicitedusingtheSGorTTO,havelargelyignoredBroome’srecommendation.However,aswithdecisionutilities,satis-factionratingsarelikelytobebasedonwhatevertherespondent’sattentionisdrawntoatthetimeoftheassessment.

Inparticular,suchratingswillbedeterminedbythecomparisonspeoplemakebetweentheirownlifeorhealthatdifferenttimes,andbetweenthemselvesandotherpeople(DolanandWhite,2006).Soakeyquestionabouttheusefulnessofsatisfactionratingsinpolicysettingsiswhetherthesecomparisonprocessesareanimportantpartofutilityintheirownrightorunhelpfuldistortionsofexperiencedutility.Theanswerwouldseemtodependontheextenttowhichtheassessmentquestiontapsintocomparisonsthattheindividualroutinelymakesinthemoment-to-momentexperienceofhislife.Putthisway,itwouldseemthatglobalassessmentsguiderespondentstomakecomparisonsthatmaynotbethefocusofattentionintheexperienceoftheirlives,oratleastnottotheextentthattheiranswertosatisfactionquestionswouldsuggest.Inaddition,satisfactionratingsarelikelytoreflectÔjudgementsthatindividualsformonthespot,basedoninformationthatischronicallyortemporarilyaccessibleatthatpointintime,resultinginpronouncedcontexteffectsÕ(SchwarzandStrack,1999).Forthesereasons,satisfactionratingsmaynotprovidethebestproxiesforthekindofexperiencedutilitywehaveinmindhere,andweinsteadneedtodevelopmeasuresof(orbetterapproximationsfor)utilityonamoment-to-momentbasis.Experiencesamplingmethods(ESM)(Stoneetal.,1999)andthedayreconstructionmethod(DRM)(Kahnemanetal.,2004)providepromisingwaysofdoingthis.ESMtypicallyinvolvesusingpalmpilotsthataskpeopleatrandomtimesduringthedaytoratedifferentfeelings(happiness,frustration,worryetc.).However,thismethodis

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invasive,itmayinterrupttheflowofanexperienceandthereareoftenmissingobservations,whichmaybenon-random(CsikszentmihalyiandHunter,2003).

TheDRMhasbeendevelopedtoovercometheseproblems,andasksrespondentstodividethepreviousdayintoanumberofepisodesandthentoratedifferentelementsofaffectduringthoseactivitiesona0–6scale.Usingthismethod,Kahnemanetal.(2004)showthatoneofthebiggestdeterminantsofgoodfeelingsissleepquality,whereasmaritalstatusandincomehavemuchsmallereffects.Largesamplescanbecollectedinarelativelyshortperiodoftimeandthemethoddoesnotdisturbtheflowofexperienceasithappens.Kahnemanetal.(2004)provideevidencethattheresultsfromtheDRMprovideagoodapproximationforthosefromtheESM.

Toproducedatathatallowtherelativecost-effectivenessofdifferentinterventionstobecalculatedrequiresthedatafromtheDRMtobeexpressedonacardinalscale.Atpresent,respondentsratearangeoffeelings,includinghappiness,worry,andfrus-tration,andthereisnowaytodeterminetherelativeweightsthateachrespondentattachestoeachofthese.OnesimplerulethatKahnemanandKrueger(2006)proposeistolookatthefeelingthatgetsthehighestrating:ifthisisanegativeone,scorethetimeinthatactivityasone;otherwisescoreitaszero.Itisthenpossibletocalculatetheproportionoftimethatpeoplespendinanunpleasantstate(whichKahnemanandKruegerrefertoastheÔU-IndexÕ).

TheDRMcanbeadministeredtopopulationswitharangeofhealthconditionsandatvariousstagesofdiseaseprogression.Bygatheringdataonpeople’shealthexperi-ences,aswellasdataonage,sexetc.,itwillbepossibletoshowhowtheactivitiespeopleengagein,andthemoment-to-momentutilityassociatedwiththoseactivities,areaffectedbytheirhealthstate.Thegreatadvantageofdataofthiskindisthatitshowswhataffectswhatpeopledoandhowtheyfeelonamoment-to-momentbasisratherthanreflectingwhatrespondentsthinkaffectsthematthetimeadecisionutilityorlifesatisfactionratingiselicited.

Bycollectingrelevantbackgroundinformation,itwillbepossibletoshowhowarangeofhealth-relatedfactors(includinganycostsassociatedwithadaptation)affectexperiencedutilitywithouttherespondenthavingtoattributetheutilitytheyexperi-enceinanyway.Indeed,themethodcouldbeusedtoshowhowarangeoffactors,includingmarketandnon-marketgoodsandservices,affectexperiencedutility.Inanyoftheseapplications,therewouldbeclearadvantagestogatheringlongitudinaldatawherepossible.Aswellasallowingtheimpactofdifferentconditionstobetracedovertime,suchstudieswouldalsoallowforissuesofcausalitytobeaddressedand,thus,facilitateabetterunderstandingofthedegreetowhichdifferentlevelsandtypesofaffectareabletopredictfuturechangesinhealth.

Werecognisethatthemeasureofexperiencedutilityweproposemaynotcaptureeverythingthatindividuals(letalonepolicymakers)aretryingtoachieve.Themethod,asitcurrentlystands,doeslittletoincorporateourhigherorderpreferencesthatgiveusoursenseofidentityanddefinewhoweare,anditignoresanypreferenceswemayhaveoverparticulartypesofhedonicexperience(Kelman,2005).Wemayalsomakejudgementsaboutthepurposeandmeaninginourlivesthatmaytranscendourhedonicexperiences(Seligman,2002).Moreover,manypeoplewouldseeminglychooseaÔrealÕlife,withitsassociatedpainandsuffering,overalifewithgreaterhedonicexperienceifthatlatterlifeweretobeartificiallycreatedbyanÔexperience

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machineÕ(Nozick,1971).Ofcourse,therehasbeen,andwillcontinuetobe,muchdebateabouttheseissues,buttheDRMcouldbeaugmentedtoaccountforsomeoftheseconsiderations.Forexample,questionscouldbeaddedabouttheimportantgoalsthatpeoplehaveandhowcertainactivitiescontributetowardsthem,andanÔextendedU-IndexÕcouldbecalculatedastheproportionoftimethatpeoplespendinpursuitoftheirgoals.

6.ConcludingRemarks

Modernwelfareeconomicsinterpretsaperson’sutilityintermsofherpreferences,andthemethodsthateconomistsanddecisionanalystshaveusedtoelicitutilityreflectthisinterpretation.Thechoicesthatrespondentsmakeinhealthstatevaluationandotherstudiesshouldbeguidedbyaccurateassessmentsoftheutilityassociatedwiththeconsequencesofthosechoices.Evenifpeopleweretoobeytheaxiomsofrationalchoiceintheirpreferencesoverhealthstates,theirpreferenceswillstillbesub-optimaliftheyaremistakenintheirforecastsoftheutilitytheywillexperienceinthefuture(Loewensteinetal.,2003).Byandlarge,itappearsthatpeopleadapttochangesintheircircumstancesbuttheyoftenfailtoappreciatethedegreetowhichtheywilladapttothosechanges.Totheextentthatourwants,ascapturedbyourdecisions,arebasedonpredictionsofwhatwewillsubsequentlyenjoy,weareoftenguiltyofÔmiswantingÕi.e.wewantthingsthatdonotmakeushappierorwedonotwantthingsthatwouldmakeushappier(GilbertandWilson,2000).

Althoughmanyeconomists,aswellasaconsensuspanelconvenedbytheUSPublicHealthService(Goldetal.,1996),recommendtheuseofutilitiesfromthegeneralpublic,elicitingdecisionutilitiesfromthosecurrentlyexperiencingthehealthstateinquestionwillavoidsomeoftheproblemsassociatedwithelicitingdecisionutilitiesfromthepublic.However,apatient’sdecisionutilitywillstillreflectwhattheywantrightnowandmaystillnotreflectthefutureutilityassociatedwiththeirhealthstate.Inshort,therearegoodreasonstosupposethathealthymembersofthegeneralpublicwillfocusonthetransitionallossinutilityassociatedwithachangeinhealthandignoretheadaptationthattakesplace,andthatpatientswillfocusontheadaptedlevelsofwell-beingandignoreanytransitionalloss.21Thatdecisionutilityandexperiencedutilitydonotproducethesameresultsshouldnotcomeasagreatsurprisetoeconomists:AdamSmith(1759)arguedthatÔThegreatsourceofboththemiseryanddisordersofhumanlifeseemstoarisefromover-ratingthedifferencebetweenonepermanentsituationandanotherÕ.Thehealthstateutilitiesthatarecurrentlyusedasthequality-adjustmentweightsinQALYscertainlyresultindifferencesbetweenfullhealthanddysfunctionalstatesthatareover-rated,andmayalsodistortthedifferencesbetweendysfunctionalstates.

Torepresenttheeffectofdifferenthealthstatesonpeople’swell-beingmoreaccu-rately,weproposethateconomistsinhealthandelsewhereshifttheirattentionfromthemeasurementofdecisionutilitytowardsthemeasurementofexperiencedutility.

Thereisthepossibilitythatpatientsmayoverstatetransitionallossesiftheythoughtthatbydoingsotherewouldbemoreresourcesdevotedtothetreatmentoftheirconditionbutthereisnoevidencethatrespondentsthinkinthisstrategicway.

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Wehavesuggestedawayinwhichthismightbedonethatrequirespeopletostatehowtheyfeltduringvariousactivitiesonthepreviousday.Themethodisarecentdevel-opmentanditssuccessfuluseinfutureempiricalstudiesinhealthandelsewherewillrequireaninterdisciplinaryapproachinvolvingeconomistsandpsychologists,andotherswithexpertiseinparticularapplications(suchascliniciansinthecaseofhealth).Wehopethatsomeoftheideaspresentedinthisarticleprovideacatalystforthisendeavour.

ImperialCollegeLondonPrincetonUniversitySubmitted:14April2005Accepted:16October2006

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